ADC Therapeutics
ADCT’s CEO Ameet Mallik participated in a fireside chat at the Guggenheim SMID Cap Biotech Conference.
Elevation Oncology
Elevation announced that members of management will participate in TD Cowen 45th Annual Health Care Conference and in Leerink Global Biopharma Conference.
Mersana Therapeutics
Mersana announced that members of management participated in a fireside chat at the Guggenheim SMID Cap Biotech Conference.
Sutro Biopharma
Short interest of Sutro increased by 15 % to 4,412,213 reported on February 14, compared to 3,850,554 on January 15.
ImmunityBio
ImmunityBio announced the FDA has granted Regenerative Medicine Advanced Therapy (RMAT) designation for Anktiva and CAR-NK (PD-L1 t-haNK) for the reversal of lymphopenia in patients receiving SOC chemotherapy or radiotherapy and in multiply relapsed locally advanced or metastatic pancreatic cancer.
Mural Oncology
Short interest of Mural decreased by 23 % to 406,088 reported on February 14, compared to 530,235 on January 15.
Nektar Therapeutic
Nektar announced that FDA has granted Fast Track designation for rezpegaldesleukin for the treatment of adult and pediatric patients 12 years of age and older with moderate-to-severe atopic dermatitis. The company also announced it has completed target enrollment in its REZOLVE-AA Phase 2b study of rezpegaldesleukin in patients with severe-to-very-severe alopecia areata.
Werewolf Therapeutics
Werewolf announced the appointment of Anil Singhal PhD, President and CEO of Trishula Therapeutics, as a member of its board of directors.
Allogene Therapeutics
Allogene announced an expanded strategic collaboration with Foresight Diagnostics to include the development of Foresight’s minimal residual disease (MRD) assay as a companion diagnostic to identify patients with large B-cell lymphoma for treatment with cemacabtagene ansegedleucel.
Autolus Therapeutics
Short interest of Autolus increased by 13 % to 9,491,664 reported on February 14, compared to 8,381,606 on January 15.
Arcellx
Arcellx reported in its annual report net loss of $47 million and $20 million for the 4Q 2024 and 2023, respectively. Net losses were $107 million and $71 million for the full year 2024 and 2023, respectively.
Mustang Bio
Mustang announced the closing of its previously announced public offering, for the issuance and sale of an aggregate of 2,657,807 shares of its common stock at a combined public offering price of $3.01 per share. The gross proceeds from the offering were approximately $8 million. The company also announced the exit of the lease for its manufacturing facility in Worcester, Massachusetts and concurrent divestment of certain fixed assets including furniture and equipment to AbbVie Bioresearch Center for $1 million.
Arcus Biosciences
Arcus presented new data from the ARC-20 study in an oral session at the 2025 ASCO Genitourinary Cancers Symposium. The presentation highlighted safety and efficacy data from three cohorts of ARC-20, which evaluated casdatifan monotherapy in patients that had received both prior TKI and anti-PD-1 therapy. The company separately announced that it retains rights to casdatifan, as Gilead’s window to exercise its option to casdatifan has expired. With this the company announced pricing of $150 million common stock offering to fund Arcus through the anticipated data readout for PEAK-1, the Phase 3 trial for casdatifan in the immuno-oncology-experienced ccRCC setting.
Immutep
mmutep provided an update on its activities for the quarter ended December 2024. The company highlighted mature data from INSIGHT-003 in 1L NSCLC, which demonstrated an excellent 32.9-month median OS and 81.0% 24-month OS rate, significantly outperforming historical controls
MacroGenics
MacroGenics announced that the company's management will participate in TD Cowen 45th Annual Healthcare Conference, Leerink Partners 2025 Global Healthcare Conference, and Barclays 27th Global Healthcare Conference.